Israel and Iran opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday that set …

The death toll is rising as Israel and Iran traded missile strikes for a third straight day. Israel on Sunday hit targets in Tehran, including the Defense Ministry and sites it claims are tied to Iran’s nuclear program. Iranian missiles have broken through Israeli defenses, striking buildings deep inside the country. The conflict began Friday with a surprise Israeli assault that killed several top Iranian generals and nuclear scientists. Israel says it is acting to stop Iran from developing nuclear bombs. The attacks follow weeks of growing tensions over Iran's enrichment of nuclear material. Iran on Thursday announced plans to activate a third nuclear enrichment site, just hours after the U.N. nuclear watchdog censured Tehran for violating nonproliferation rules.

Israel unleashed airstrikes across Iran for a third day and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country. Planned talks on Iran’s nuclear program, which could provide an off-ramp, were called off. The region braced for a protracted conflict after Israel’s surprise bombardment of Iran’s nuclear and military sites on Friday killed several top generals and nuclear scientists, and neither side showed any sign of backing down. Israel reportedly targeted a gas installation, raising the prospect of a broader assault on Iran’s heavily-sanctioned energy industry that could affect global markets.

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